Company / FCF Margin
IONIS PHARMACEUTICALS INC FCF Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest FCF Margin
-33.9%
FY2025
5-year range
-241.1% / 71.5%
FY2021-FY2025
Trend
+85.9%
vs FY2024
Sector context
#79 of 133
Health Care
What the data says
At -33.9%, IONIS PHARMACEUTICALS INC's fcf margin ranks #79 of 133 in the Health Care sector. FCF Margin has fluctuated over the past 10 years, ranging from -241.1% in FY2024 to 203.0% in FY2020.
Based on SEC 10-K filings.
-33.9% in FY2025 with a 5-year CAGR of -236.9%.
Improved from -102.1% to -33.9% over the past 2 years.
Health Care sector context is included.
FCF Margin over time
Growth rates
- 3-Year Change
- +157.1pp
- 5-Year Change
- -236.9pp
- 10-Year Change
- -
Sector benchmark
#79 of 133 in Health CareTop 59% of 133This company -33.9% Sector average -632.8%
▼
+94.6% above sector average
Key checks
Key Insights
- In FY2025, fcf margin increased 85.9% year-over-year.
- Currently 598.9pp above the Health Care sector average.
- Peak fcf margin was recorded in FY2020.
- Lowest fcf margin in the period was in FY2024.
Company context
Key Data Points
- Altman Z-Score -0.18 (distress zone, below 1.8 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | FCF MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -33.9% | +85.9% |
| FY2024 | -241.1% | -136.1% |
| FY2023 | -102.1% | +46.5% |
| FY2022 | -191.0% | -367.0% |
| FY2021 | 71.5% | -64.8% |
| FY2020 | 203.0% | +619.1% |
| FY2019 | 28.2% | +134.2% |
| FY2018 | -82.5% | -165.3% |
| FY2017 | 126.4% | +467.4% |
| FY2016 | -34.4% | -827.1% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026