Company / Free Cash Flow
IONIS PHARMACEUTICALS INC Free Cash Flow History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Free Cash Flow
-$320.0M
FY2025
5-year range
-$546.2M / $314.7M
FY2021-FY2025
Trend
+41.4%
vs FY2024
Sector context
#171 of 194
Health Care
What the data says
IONIS PHARMACEUTICALS INC's free cash flow of -$320M is lower than 88% of companies in the Health Care sector (FY2025). Free Cash Flow returned to growth in FY2025 after 4 years of decline, reaching -$320M.
Based on SEC 10-K filings.
-$320M in FY2025.
Improved from -$331M to -$320M over the past 2 years.
Health Care sector context is included.
Free Cash Flow over time
Growth rates
- 3-Year CAGR
- -
- 5-Year CAGR
- -
- 10-Year CAGR
- -
Sector benchmark
Bottom 12% in Health CareTop 88% of 194This company -$320.0M Sector average $470.8M
▼
-168.0% below sector average
Key checks
Key Insights
- In FY2025, free cash flow increased 41.4% year-over-year.
- Ranks #171 out of 194 companies in the Health Care sector.
- Peak free cash flow was recorded in FY2020.
- Lowest free cash flow in the period was in FY2024.
Company context
Key Data Points
- Altman Z-Score -0.18 (distress zone, below 1.8 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Free Cash FlowValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -$320.0M | +41.4% |
| FY2024 | -$546.2M | -64.9% |
| FY2023 | -$331.3M | -14.2% |
| FY2022 | -$290.1M | -192.2% |
| FY2021 | $314.7M | -46.6% |
| FY2020 | $589.3M | +322.8% |
| FY2019 | $139.4M | +216.9% |
| FY2018 | -$119.2M | -185.5% |
| FY2017 | $139.4M | +216.9% |
| FY2016 | -$119.2M | -987.5% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026