Company / Profit Margin
Spyre Therapeutics, Inc. Profit Margin History
FY2018-FY2023 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Profit Margin
-38238.2%
FY2023
5-year range
-38238.2% / -351.1%
FY2019-FY2023
Trend
-
vs FY2022
Sector context
#146 of 146
Health Care
What the data says
Profit Margin changed -10790% YoY in FY2023, a notable deviation from the 4-year average annual change of -2713%.
Based on SEC 10-K filings.
-38238.2% in FY2023 with a 5-year CAGR of -37769.3%.
Declined from -1140.6% to -38238.2% over the past 3 years.
Health Care sector context is included.
Profit Margin over time
Growth rates
- 3-Year Change
- -37097.5pp
- 5-Year Change
- -37769.3pp
- 10-Year Change
- -
Sector benchmark
Bottom 0% in Health CareTop 100% of 146This company -38238.2% Sector average -796.3%
▼
-4702.2% below sector average
Key checks
Key Insights
- Currently 37441.9pp below the Health Care sector average.
- Peak profit margin was recorded in FY2021.
Company context
Key Data Points
- Low Piotroski F-Score: 2/9 (multiple financial health concerns)
- Altman Z-Score 3.40 (safe zone, above 2.9 threshold)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Profit MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | - | - |
| FY2024 | - | - |
| FY2023 | -38238.2% | - |
| FY2022 | - | - |
| FY2021 | -351.1% | +69.2% |
| FY2020 | -1140.6% | -118.0% |
| FY2019 | -523.3% | -11.6% |
| FY2018 | -468.8% | - |
| FY2017 | - | - |
| FY2016 | - | - |
As of FY2023 · SEC 10-K · Updated Jun 30, 2026