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Spyre Therapeutics, Inc.
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Financials

Company / Financials

Spyre Therapeutics, Inc. Financials

FY2016-FY2025 · Annual data · Source: SEC filings

At a glance

Latest annual filing available

Revenue

$0

FY2025

Net Income

-$155.2M

FY2025 · +25.4% YoY

Profit Margin

-

FY2025 · net income / revenue

ROE

-21.7%

FY2025 · return on equity

Total Assets

$777.8M

FY2025

Total Debt

-

FY2025

Equity

$715.2M

FY2025

ROA

-20.0%

FY2025 · return on assets

New to financial statements? Read the quick guide.Open

Statement paths

Income StatementRevenue, expenses, margins, and profit.View Balance SheetAssets, debt, liabilities, and equity.View Cash Flow StatementCash generated, reinvested, and returned.View

Financial highlights

Key Data Points

Low Piotroski F-Score: 2/9 (multiple financial health concerns)
Altman Z-Score 3.40 (safe zone, above 2.9 threshold)

Data sourced from SEC EDGAR filings. Not investment advice.

Metric history

Revenue HistoryTotal revenue from operations$0 Net Income HistoryProfit after all expenses and taxes-$155.2M+25.4% YoY Operating Income HistoryProfit from core business operations before interest and taxes-$209.6M-0.5% YoY SG&A Expense HistorySelling, general, and administrative expenses$47.9M+4.7% YoY R&D Expense HistoryResearch and development spending$171.7M+5.4% YoY Income Tax HistoryTotal income tax expense-$15.0K-129.4% YoY EPS (Basic) HistoryBasic earnings per share-$25.02 EPS (Diluted) HistoryDiluted earnings per share including stock options and convertibles-$25.02 Shares Outstanding HistoryWeighted average diluted shares outstanding60.3M+67.1% YoY Total Assets HistoryTotal value of all assets owned$777.8M+27.8% YoY

Continue your research

Income StatementRevenue, expenses, margins, and profit.View Balance SheetAssets, debt, liabilities, and equity.View Cash Flow StatementCash generated, reinvested, and returned.View Financial RatiosMargin, return, leverage, and DuPont context.View Piotroski F-ScoreNine checks for profitability, leverage, and efficiency.View Altman Z-ScoreA bankruptcy-risk model built from financial statements.View

Data basis

10 annual filings shown

Primary company stock selected

SEC annual filings used as source

Financial data is for research and education. This is not investment advice.

Back to Spyre Therapeutics, Inc. overview

Data Sources

SEC 10-K Annual Filings

FY2025· Updated Jun 30, 2026

System data refreshed: Jul 2, 2026

For informational purposes only. Not investment advice. Past performance is not indicative of future results. Data sourced from SEC EDGAR filings. Consult a qualified financial advisor before making investment decisions.