Company / Operating Margin
Spyre Therapeutics, Inc. Operating Margin History
FY2018-FY2023 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
-27348.0%
FY2023
5-year range
-27348.0% / -350.3%
FY2019-FY2023
Trend
-
vs FY2022
Sector context
#136 of 136
Health Care
What the data says
Operating Margin changed -7706% YoY in FY2023, a notable deviation from the 4-year average annual change of -1942%.
Based on SEC 10-K filings.
-27348.0% in FY2023 with a 5-year CAGR of -26874.6%.
Declined from -1169.3% to -27348.0% over the past 3 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- -26178.6pp
- 5-Year Change
- -26874.6pp
- 10-Year Change
- -
Sector benchmark
Bottom 0% in Health CareTop 100% of 136This company -27348.0% Sector average -778.9%
▼
-3411.0% below sector average
Key checks
Key Insights
- Currently 26569.0pp below the Health Care sector average.
- Peak operating margin was recorded in FY2021.
Company context
Key Data Points
- Low Piotroski F-Score: 2/9 (multiple financial health concerns)
- Altman Z-Score 3.40 (safe zone, above 2.9 threshold)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | - | - |
| FY2024 | - | - |
| FY2023 | -27348.0% | - |
| FY2022 | - | - |
| FY2021 | -350.3% | +70.0% |
| FY2020 | -1169.3% | -119.9% |
| FY2019 | -531.7% | -12.3% |
| FY2018 | -473.3% | - |
| FY2017 | - | - |
| FY2016 | - | - |
As of FY2023 · SEC 10-K · Updated Jun 30, 2026