Company / Net Income
IONIS PHARMACEUTICALS INC Net Income History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Net Income
-$381.4M
FY2025
5-year range
-$453.9M / $278.1M
FY2021-FY2025
Trend
+16.0%
vs FY2024
Sector context
#192 of 216
Health Care
What the data says
IONIS PHARMACEUTICALS INC's net income of -$381M is lower than 89% of companies in the Health Care sector (FY2025). Net Income returned to growth in FY2025 after 3 years of decline, reaching -$381M.
Based on SEC 10-K filings.
-$381M in FY2025.
Declined from -$366M to -$381M over the past 2 years.
Health Care sector context is included.
Net Income over time
Growth rates
- 3-Year CAGR
- -
- 5-Year CAGR
- -
- 10-Year CAGR
- -
Sector benchmark
Bottom 11% in Health CareTop 89% of 216This company -$381.4M Sector average $454.1M
▼
-184.0% below sector average
Key checks
Key Insights
- In FY2025, net income increased 16.0% year-over-year.
- Ranks #192 out of 216 companies in the Health Care sector.
- Peak net income was recorded in FY2021.
- Lowest net income in the period was in FY2024.
Company context
Key Data Points
- Altman Z-Score -0.18 (distress zone, below 1.8 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Net IncomeValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -$381.4M | +16.0% |
| FY2024 | -$453.9M | -23.9% |
| FY2023 | -$366.3M | -35.8% |
| FY2022 | -$269.7M | -197.0% |
| FY2021 | $278.1M | +1.6% |
| FY2020 | $273.7M | +79015.9% |
| FY2019 | $346.0K | +100.6% |
| FY2018 | -$60.4M | -17556.6% |
| FY2017 | $346.0K | +100.6% |
| FY2016 | -$60.4M | +31.6% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026