Company / Profit Margin
AGIOS PHARMACEUTICALS, INC. Profit Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Profit Margin
-764.0%
FY2025
5-year range
-1312.6% / 1845.9%
FY2021-FY2025
Trend
-141.4%
vs FY2024
Sector context
#125 of 145
Health Care
What the data says
AGIOS PHARMACEUTICALS, INC.'s profit margin of -764.0% is lower than 86% of companies in the Health Care sector (FY2025). Profit Margin has fluctuated over the past 8 years, ranging from -2994.6% in FY2017 to 1845.9% in FY2024.
Based on SEC 10-K filings.
-764.0% in FY2025 with a 5-year CAGR of -397.4%.
Improved from -1312.6% to -764.0% over the past 2 years.
Health Care sector context is included.
Profit Margin over time
Growth rates
- 3-Year Change
- -
- 5-Year Change
- -397.4pp
- 10-Year Change
- -
Sector benchmark
Bottom 14% in Health CareTop 86% of 145This company -764.0% Sector average -792.7%
▼
+3.6% above sector average
Key checks
Key Insights
- In FY2025, profit margin decreased 141.4% year-over-year.
- Currently 28.7pp above the Health Care sector average.
- Peak profit margin was recorded in FY2024.
- Lowest profit margin in the period was in FY2017.
Company context
Key Data Points
- Low Piotroski F-Score: 2/9 (multiple financial health concerns)
- Altman Z-Score 3.83 (safe zone, above 2.9 threshold)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Profit MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -764.0% | -141.4% |
| FY2024 | 1845.9% | +240.6% |
| FY2023 | -1312.6% | - |
| FY2022 | - | - |
| FY2021 | - | - |
| FY2020 | -366.6% | -5.1% |
| FY2019 | -349.0% | -22.9% |
| FY2018 | -284.0% | +90.5% |
| FY2017 | -2994.6% | -954.5% |
| FY2016 | -284.0% | -146.5% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026