Company / Operating Margin
AGIOS PHARMACEUTICALS, INC. Operating Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
-873.9%
FY2025
5-year range
-1459.5% / -873.9%
FY2021-FY2025
Trend
+25.1%
vs FY2024
Sector context
#117 of 135
Health Care
What the data says
AGIOS PHARMACEUTICALS, INC.'s operating margin of -873.9% is lower than 87% of companies in the Health Care sector (FY2025). Operating Margin has fluctuated over the past 8 years, ranging from -3052.8% in FY2017 to -268.2% in FY2019.
Based on SEC 10-K filings.
-873.9% in FY2025 with a 5-year CAGR of -489.8%.
Improved from -1459.5% to -873.9% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- -
- 5-Year Change
- -489.8pp
- 10-Year Change
- -
Sector benchmark
Bottom 13% in Health CareTop 87% of 135This company -873.9% Sector average -774.4%
▼
-12.8% below sector average
Key checks
Key Insights
- In FY2025, operating margin increased 25.1% year-over-year.
- Currently 99.4pp below the Health Care sector average.
- Peak operating margin was recorded in FY2019.
- Lowest operating margin in the period was in FY2017.
Company context
Key Data Points
- Low Piotroski F-Score: 2/9 (multiple financial health concerns)
- Altman Z-Score 3.83 (safe zone, above 2.9 threshold)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -873.9% | +25.1% |
| FY2024 | -1166.5% | +20.1% |
| FY2023 | -1459.5% | - |
| FY2022 | - | - |
| FY2021 | - | - |
| FY2020 | -384.0% | -43.2% |
| FY2019 | -268.2% | +6.7% |
| FY2018 | -287.6% | +90.6% |
| FY2017 | -3052.8% | -961.6% |
| FY2016 | -287.6% | -152.9% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026