Company / Operating Margin
Wave Life Sciences Ltd. Operating Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
-504.1%
FY2025
5-year range
-763.9% / -60.0%
FY2021-FY2025
Trend
-394.5%
vs FY2024
Sector context
#112 of 136
Health Care
What the data says
Operating Margin changed -394% YoY in FY2025, a notable deviation from the 9-year average annual change of -65%.
Based on SEC 10-K filings.
-504.1% in FY2025 with a 5-year CAGR of +799.3%.
Declined from -60.0% to -504.1% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- -194.0pp
- 5-Year Change
- +799.3pp
- 10-Year Change
- -
Sector benchmark
Bottom 18% in Health CareTop 82% of 136This company -504.1% Sector average -778.9%
▼
+35.3% above sector average
Key checks
Key Insights
- In FY2025, operating margin decreased 394.5% year-over-year.
- Currently 274.8pp above the Health Care sector average.
- Peak operating margin was recorded in FY2023.
- Lowest operating margin in the period was in FY2017.
Company context
Key Data Points
- Low Piotroski F-Score: 2/9 (multiple financial health concerns)
- Altman Z-Score -0.34 (distress zone, below 1.8 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -504.1% | -394.5% |
| FY2024 | -101.9% | -69.9% |
| FY2023 | -60.0% | +80.6% |
| FY2022 | -310.1% | +59.4% |
| FY2021 | -763.9% | +41.4% |
| FY2020 | -1303.4% | +50.4% |
| FY2019 | -2630.1% | -137.7% |
| FY2018 | -1106.7% | +92.7% |
| FY2017 | -15146.6% | -303.7% |
| FY2016 | -3752.2% | +72.7% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026