Company / Operating Margin
Vertex Pharmaceuticals Operating Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
34.8%
FY2025
5-year range
-2.1% / 48.2%
FY2021-FY2025
Trend
+1747.9%
vs FY2024
Sector context
#13 of 136
Health Care
What the data says
Operating Margin changed +1748% YoY in FY2025, a notable deviation from the 9-year average annual change of +514%.
Based on SEC 10-K filings.
34.8% in FY2025 with a 5-year CAGR of -11.3%. Top quartile in the Health Care sector.
Declined from 38.8% to 34.8% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- -13.5pp
- 5-Year Change
- -11.3pp
- 10-Year Change
- -
Sector benchmark
Top 10% in Health CareTop 10% of 136This company 34.8% Sector average -778.9%
▼
+104.5% above sector average
Key checks
Key Insights
- In FY2025, operating margin increased 1747.9% year-over-year.
- Currently 813.7pp above the Health Care sector average.
- Peak operating margin was recorded in FY2022.
- Lowest operating margin in the period was in FY2024.
Company context
Key Data Points
- Strong profit margin: 31.4%
- Strong return on equity: 21.2%
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | 34.8% | +1747.9% |
| FY2024 | -2.1% | -105.4% |
| FY2023 | 38.8% | -19.5% |
| FY2022 | 48.2% | +31.3% |
| FY2021 | 36.7% | -20.2% |
| FY2020 | 46.0% | +60.0% |
| FY2019 | 28.8% | +38.1% |
| FY2018 | 20.8% | +20.9% |
| FY2017 | 17.2% | +2872.4% |
| FY2016 | 0.6% | +101.3% |
As of FY2025 · SEC 10-K · Updated Mar 17, 2026