Company / Net Income
Upstream Bio, Inc. Net Income History
FY2023-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Net Income
-$143.4M
FY2025
5-year range
-$143.4M / -$20.5M
FY2023-FY2025
Trend
-598.5%
vs FY2024
Sector context
#127 of 216
Health Care
What the data says
Net Income changed -598% YoY in FY2025, a notable deviation from the 2-year average annual change of -299%.
Based on SEC 10-K filings.
-$143M in FY2025.
Declined from -$21M to -$143M over the past 2 years.
Health Care sector context is included.
Net Income over time
Growth rates
- 3-Year CAGR
- -
- 5-Year CAGR
- -
- 10-Year CAGR
- -
Sector benchmark
#127 of 216 in Health CareTop 59% of 216This company -$143.4M Sector average $454.3M
▼
-131.6% below sector average
Key checks
Key Insights
- In FY2025, net income decreased 598.5% year-over-year.
- Ranks #127 out of 216 companies in the Health Care sector.
Company context
Key Data Points
- Low Piotroski F-Score: 2/9 (multiple financial health concerns)
- Altman Z-Score 8.68 (safe zone, above 2.9 threshold)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Net IncomeValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -$143.4M | -598.5% |
| FY2024 | -$20.5M | +0.0% |
| FY2023 | -$20.5M | - |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026