Company / Profit Margin
Ultragenyx Pharmaceutical Inc. Profit Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Profit Margin
-85.4%
FY2025
5-year range
-388.3% / -85.4%
FY2021-FY2025
Trend
+15.9%
vs FY2024
Sector context
#96 of 146
Health Care
What the data says
At -85.4%, Ultragenyx Pharmaceutical Inc.'s profit margin ranks #96 of 146 in the Health Care sector. Profit Margin has increased for 4 consecutive years, from -388.3% in FY2021 to -85.4% in FY2025.
Based on SEC 10-K filings.
-85.4% in FY2025 with a 5-year CAGR of +298.3%.
Improved from -139.9% to -85.4% over the past 2 years.
Health Care sector context is included.
Profit Margin over time
Growth rates
- 3-Year Change
- +109.3pp
- 5-Year Change
- +298.3pp
- 10-Year Change
- -
Sector benchmark
#96 of 146 in Health CareTop 66% of 146This company -85.4% Sector average -796.3%
▼
+89.3% above sector average
Key checks
Key Insights
- Ultragenyx Pharmaceutical Inc.'s profit margin has grown for 4 consecutive years.
- In FY2025, profit margin increased 15.9% year-over-year.
- Currently 710.8pp above the Health Care sector average.
- Lowest profit margin in the period was in FY2016.
Company context
Key Data Points
- Altman Z-Score -2.91 (distress zone, below 1.8 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Profit MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -85.4% | +15.9% |
| FY2024 | -101.6% | +27.3% |
| FY2023 | -139.9% | +28.2% |
| FY2022 | -194.7% | +49.9% |
| FY2021 | -388.3% | -1.2% |
| FY2020 | -383.8% | +96.7% |
| FY2019 | -11567.3% | -2914.3% |
| FY2018 | -383.8% | +99.6% |
| FY2017 | -109487.2% | +68.9% |
| FY2016 | -351776.5% | - |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026