Company / Operating Margin
Syndax Pharmaceuticals Inc Operating Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
-158.4%
FY2025
5-year range
-3792.9% / -158.4%
FY2021-FY2025
Trend
+89.0%
vs FY2024
Sector context
#95 of 136
Health Care
What the data says
At -158.4%, Syndax Pharmaceuticals Inc's operating margin ranks #95 of 136 in the Health Care sector. Operating Margin has increased for 3 consecutive years, from -5001.7% in FY2020 to -158.4% in FY2025.
Based on SEC 10-K filings.
-158.4% in FY2025 with a 5-year CAGR of +4843.3%.
Improved from -3792.9% to -158.4% over the past 4 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- -
- 5-Year Change
- +4843.3pp
- 10-Year Change
- -
Sector benchmark
#95 of 136 in Health CareTop 70% of 136This company -158.4% Sector average -778.9%
▼
+79.7% above sector average
Key checks
Key Insights
- In FY2025, operating margin increased 89.0% year-over-year.
- Currently 620.5pp above the Health Care sector average.
- Lowest operating margin in the period was in FY2020.
Company context
Key Data Points
- Low Piotroski F-Score: 1/9 (multiple financial health concerns)
- Altman Z-Score -3.08 (distress zone, below 1.8 threshold)
- Low earnings quality (accrual-heavy earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -158.4% | +89.0% |
| FY2024 | -1434.4% | - |
| FY2023 | - | - |
| FY2022 | - | - |
| FY2021 | -3792.9% | +24.2% |
| FY2020 | -5001.7% | -70.2% |
| FY2019 | -2939.0% | +18.1% |
| FY2018 | -3587.4% | -9.7% |
| FY2017 | -3271.6% | +3.8% |
| FY2016 | -3402.2% | - |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026