Company / Operating Income
Protagonist Therapeutics, Inc. Operating Income History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Income
-$158.1M
FY2025
5-year range
-$158.1M / $252.8M
FY2021-FY2025
Trend
-162.5%
vs FY2024
Sector context
#118 of 204
Health Care
What the data says
At -$158M, Protagonist Therapeutics, Inc.'s operating income ranks #118 of 204 in the Health Care sector. Operating Income has fluctuated over the past 10 years, ranging from -$158M in FY2025 to $253M in FY2024.
Based on SEC 10-K filings.
-$158M in FY2025.
Declined from -$94M to -$158M over the past 2 years.
Health Care sector context is included.
Operating Income over time
Growth rates
- 3-Year CAGR
- -
- 5-Year CAGR
- -
- 10-Year CAGR
- -
Sector benchmark
#118 of 204 in Health CareTop 58% of 204This company -$158.1M Sector average $107.7M
▼
-246.8% below sector average
Key checks
Key Insights
- In FY2025, operating income decreased 162.5% year-over-year.
- Ranks #118 out of 204 companies in the Health Care sector.
- Peak operating income was recorded in FY2024.
Company context
Key Data Points
- Altman Z-Score 4.66 (safe zone, above 2.9 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating IncomeValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -$158.1M | -162.5% |
| FY2024 | $252.8M | +370.0% |
| FY2023 | -$93.7M | +28.7% |
| FY2022 | -$131.4M | -4.4% |
| FY2021 | -$125.8M | -95.1% |
| FY2020 | -$64.5M | +19.9% |
| FY2019 | -$80.5M | -90.5% |
| FY2018 | -$42.3M | -11.5% |
| FY2017 | -$37.9M | -16.0% |
| FY2016 | -$32.7M | -120.8% |
As of FY2025 · SEC 10-K · Updated Feb 28, 2026