Company / Operating Margin
Personalis, Inc. Operating Margin History
FY2018-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
-126.4%
FY2025
5-year range
-177.6% / -76.4%
FY2021-FY2025
Trend
+15.5%
vs FY2024
Sector context
#143 of 148
Health Care
What the data says
Among 148 Health Care companies, Personalis, Inc. is in the bottom 3% for operating margin. Operating Margin has fluctuated over the past 8 years, ranging from -236.0% in FY2019 to -36.4% in FY2020.
Based on SEC 10-K filings.
-126.4% in FY2025 with a 5-year CAGR of -90.0%.
Declined from -76.4% to -126.4% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- +51.2pp
- 5-Year Change
- -90.0pp
- 10-Year Change
- -
Sector benchmark
Bottom 3% in Health CareTop 97% of 148This company -126.4% Sector average -284.8%
▼
+55.6% above sector average
Key checks
Key Insights
- In FY2025, operating margin increased 15.5% year-over-year.
- Currently 158.3pp above the Health Care sector average.
- Peak operating margin was recorded in FY2020.
- Lowest operating margin in the period was in FY2019.
Company context
Key Data Points
- Altman Z-Score -0.22 (distress zone, below 1.8 threshold)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | -126.4% | +15.5% |
| FY2024 | -149.6% | -95.7% |
| FY2023 | -76.4% | +57.0% |
| FY2022 | -177.6% | -132.4% |
| FY2021 | -76.4% | -109.7% |
| FY2020 | -36.4% | +84.6% |
| FY2019 | -236.0% | -547.3% |
| FY2018 | -36.5% | - |
| FY2017 | - | - |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026