Company / Operating Margin
Illumina, Inc. Operating Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
18.6%
FY2025
5-year range
-23.7% / 18.6%
FY2021-FY2025
Trend
+197.5%
vs FY2024
Sector context
#20 of 148
Health Care
What the data says
Illumina, Inc.'s operating margin of 18.6% is higher than 86% of companies in the Health Care sector (FY2025). Operating Margin has fluctuated over the past 10 years, ranging from -23.7% in FY2023 to 27.6% in FY2017.
Based on SEC 10-K filings.
18.6% in FY2025 with a 5-year CAGR of +0.7%. Top quartile in the Health Care sector.
Improved from -23.7% to 18.6% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- +0.7pp
- 5-Year Change
- +0.7pp
- 10-Year Change
- -
Sector benchmark
+106.5% above sector average
Key checks
Key Insights
- In FY2025, operating margin increased 197.5% year-over-year.
- Currently 303.4pp above the Health Care sector average.
- Peak operating margin was recorded in FY2017.
- Lowest operating margin in the period was in FY2023.
Company context
Key Data Points
- High earnings quality (cash-backed earnings)
- Strong return on equity: 29.5%
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | 18.6% | +197.5% |
| FY2024 | -19.1% | +19.7% |
| FY2023 | -23.7% | -232.5% |
| FY2022 | 17.9% | +758.5% |
| FY2021 | -2.7% | -115.2% |
| FY2020 | 17.9% | -18.7% |
| FY2019 | 22.0% | -10.0% |
| FY2018 | 24.5% | -11.3% |
| FY2017 | 27.6% | +12.8% |
| FY2016 | 24.5% | -11.3% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026