Company / Operating Margin
Denali Therapeutics Inc. Operating Margin History
FY2020-FY2023 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
-59.5%
FY2023
5-year range
-799.1% / 18.7%
FY2020-FY2023
Trend
-418.4%
vs FY2022
Sector context
#80 of 135
Health Care
What the data says
Operating Margin changed -418% YoY in FY2023, a notable deviation from the 3-year average annual change of -814%.
Based on SEC 10-K filings.
-59.5% in FY2023 with a 3-year CAGR of -23.6%.
Improved from -799.1% to -59.5% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- -23.6pp
- 5-Year Change
- -
- 10-Year Change
- -
Sector benchmark
#80 of 135 in Health CareTop 59% of 135This company -59.5% Sector average -774.4%
▼
+92.3% above sector average
Key checks
Key Insights
- In FY2023, operating margin decreased 418.4% year-over-year.
- Currently 714.9pp above the Health Care sector average.
Company context
Key Data Points
- Low Piotroski F-Score: 2/9 (multiple financial health concerns)
- Altman Z-Score 0.73 (distress zone, below 1.8 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | - | - |
| FY2024 | - | - |
| FY2023 | -59.5% | -418.4% |
| FY2022 | 18.7% | +102.3% |
| FY2021 | -799.1% | -2125.9% |
| FY2020 | -35.9% | - |
| FY2019 | - | - |
| FY2018 | - | - |
| FY2017 | - | - |
| FY2016 | - | - |
As of FY2023 · SEC 10-K · Updated Jun 30, 2026