Company / Operating Margin
ANAPTYSBIO, INC Operating Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
20.4%
FY2025
5-year range
-1342.9% / 20.4%
FY2021-FY2025
Trend
+116.2%
vs FY2024
Sector context
#26 of 136
Health Care
What the data says
ANAPTYSBIO, INC's operating margin of 20.4% is higher than 81% of companies in the Health Care sector (FY2025). Operating Margin has fluctuated over the past 9 years, ranging from -1342.9% in FY2021 to 20.4% in FY2025.
Based on SEC 10-K filings.
20.4% in FY2025 with a 5-year CAGR of +1354.9%. Top quartile in the Health Care sector.
Improved from -958.3% to 20.4% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- +52.3pp
- 5-Year Change
- +1354.9pp
- 10-Year Change
- -
Sector benchmark
+102.6% above sector average
Key checks
Key Insights
- In FY2025, operating margin increased 116.2% year-over-year.
- Currently 799.4pp above the Health Care sector average.
- Lowest operating margin in the period was in FY2021.
Company context
Key Data Points
- Altman Z-Score -0.08 (distress zone, below 1.8 threshold)
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | 20.4% | +116.2% |
| FY2024 | -125.9% | +86.9% |
| FY2023 | -958.3% | -2909.6% |
| FY2022 | -31.8% | +97.6% |
| FY2021 | -1342.9% | -0.6% |
| FY2020 | -1334.4% | -363.7% |
| FY2019 | -287.8% | - |
| FY2018 | - | - |
| FY2017 | -18.9% | -4.3% |
| FY2016 | -18.1% | +4.1% |
As of FY2025 · SEC 10-K · Updated Jun 30, 2026