Company / Operating Margin
AMICUS THERAPEUTICS, INC. Operating Margin History
FY2016-FY2025 · Annual data · Source: SEC filings
At a glance
Latest annual filing availableLatest Operating Margin
5.2%
FY2025
5-year range
-67.6% / 5.2%
FY2021-FY2025
Trend
+9.8%
vs FY2024
Sector context
#50 of 136
Health Care
What the data says
At 5.2%, AMICUS THERAPEUTICS, INC.'s operating margin ranks #50 of 136 in the Health Care sector. Operating Margin has increased for 7 consecutive years, from -3668.6% in FY2016 to 5.2% in FY2025.
Based on SEC 10-K filings.
5.2% in FY2025 with a 5-year CAGR of +99.8%.
Improved from -19.3% to 5.2% over the past 2 years.
Health Care sector context is included.
Operating Margin over time
Growth rates
- 3-Year Change
- +69.6pp
- 5-Year Change
- +99.8pp
- 10-Year Change
- -
Sector benchmark
#50 of 136 in Health CareTop 37% of 136This company 5.2% Sector average -778.9%
▼
+100.7% above sector average
Key checks
Key Insights
- AMICUS THERAPEUTICS, INC.'s operating margin has grown for 5 consecutive years.
- In FY2025, operating margin increased 9.8% year-over-year.
- Currently 784.1pp above the Health Care sector average.
- Lowest operating margin in the period was in FY2016.
Company context
Key Data Points
- Altman Z-Score -1.19 (distress zone, below 1.8 threshold)
- Negative profit margin: -10.6%
- High earnings quality (cash-backed earnings)
Data sourced from SEC EDGAR filings. Not investment advice.
Annual data
| Year | Operating MarginValue | YoY GrowthYoY |
|---|---|---|
| FY2025 | 5.2% | +9.8% |
| FY2024 | 4.7% | +124.4% |
| FY2023 | -19.3% | +70.0% |
| FY2022 | -64.4% | +4.6% |
| FY2021 | -67.6% | +28.6% |
| FY2020 | -94.7% | - |
| FY2019 | - | - |
| FY2018 | - | - |
| FY2017 | -1196.8% | +67.4% |
| FY2016 | -3668.6% | - |
As of FY2025 · SEC 10-K · Updated Feb 28, 2026